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DNA Available
Experience: None
Part:BBa_R0062
Entered: Antiquity
Designed by Vinay S Mahajan, Voichita D. Marinescu, Brian Chow, Alexander D Wissner-Gross and Peter Carr Group: Registry
From partsregistry.org
Promoter (luxR & HSL regulated -- lux pR)
Promoter activated by LuxR in concert with HSL
The lux cassette of V. fischeri contains a left and a right promoter. The right promoter gives weak constitutive expression of downstream genes.This expression is up-regulated by the action of the LuxR activator protein complexed with the autoinducer, 3-oxo-hexanoyl-HSL. Two molecules of LuxR protein form a complex with two molecules of the signalling compound homoserine lactone (HSL). This complex binds to a palindromic site on the promoter, increasing the rate of transcription.
Usage and Biology
Pretty good off in the absence of LuxR/HSL. [jb, 5/24/04]
Sequence and Features
