Generator
tetR
Part:BBa_P1005:Design
Designed by Reshma Shetty Group: Knight Lab, MIT (2006-02-03)
From partsregistry.org
tetracycline resistance cassette
Assembly Compatibility:
- 10COMPATIBLE WITH RFC[10]
- 21COMPATIBLE WITH RFC[21]
- 23COMPATIBLE WITH RFC[23]
- 25COMPATIBLE WITH RFC[25]
Design Notes
BBa_P1005 is an tetracycline antibiotic resistance cassette. Several silent mutations were introduced to eliminate useful restriction sites and rare codons.
Source
References
- WATANABE T and FUKASAWA T. Episome-mediated transfer of drug resistance in Enterobacteriaceae. I. Transfer of resistance factors by conjugation. J Bacteriol 1961 May; 81 669-78. pmid:13783344.
- WATANABE T. Infective heredity of multiple drug resistance in bacteria. Bacteriol Rev 1963 Mar; 27 87-115. pmid:13999115.
- Anderson ES. Origin of transferable drug-resistance factors in the enterobacteriaceae. Br Med J 1965 Nov 27; 2(5473) 1289-91. pmid:5321597.
1 Registry Star
