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ampR

Part:BBa_P1002:Design

Designed by Reshma Shetty   Group: Knight Lab, MIT   (2006-01-23)

From partsregistry.org

ampicillin resistance cassette

Assembly Compatibility:
  • 10
    COMPATIBLE WITH RFC[10]
  • 21
    COMPATIBLE WITH RFC[21]
  • 23
    COMPATIBLE WITH RFC[23]
  • 25
    COMPATIBLE WITH RFC[25]


Design Notes

BBa_P1002 is an ampicillin antibiotic resistance cassette. Several silent mutations were introduced to eliminate useful restriction sites and rare codons.

Source

References

  1. WATANABE T and FUKASAWA T. Episome-mediated transfer of drug resistance in Enterobacteriaceae. I. Transfer of resistance factors by conjugation. J Bacteriol 1961 May; 81 669-78. pmid:13783344. PubMed HubMed [Watanabe-J-Bacteriol-1961]
  2. WATANABE T. Infective heredity of multiple drug resistance in bacteria. Bacteriol Rev 1963 Mar; 27 87-115. pmid:13999115. PubMed HubMed [Watanabe-Bacteriol-Rev-2003]
  3. Anderson ES. Origin of transferable drug-resistance factors in the enterobacteriaceae. Br Med J 1965 Nov 27; 2(5473) 1289-91. pmid:5321597. PubMed HubMed [Anderson-Br-Med-J-1965]
All Medline abstracts: PubMed HubMed